AOD 9604 (5mg)

$45.00

AOD-9604

AOD-9604 is a peptide that is being investigated for its potential therapeutic effects, particularly in relation to **cancer**. It’s not currently FDA-approved for any use.

**Mechanism of Action (Hypothetical):**

The exact mechanism by which AOD-9604 works is not fully understood. However, it’s believed to target cancer cells by potentially:

* **Disrupting cell growth and proliferation:** AOD-9604 may interfere with processes within cancer cells that promote their uncontrolled growth.

* **Inducing apoptosis (programmed cell death):** Research suggests a potential ability to trigger programmed cell death in cancer cells.

* **Inhibiting tumor angiogenesis (blood vessel formation):** This is a crucial component of tumor growth, and AOD-9604 may interfere with this process.

**Current Research and Clinical Trials:**

Research into AOD-9604 is ongoing, primarily focused on preclinical studies and early-stage clinical trials in cancer patients. Results from these studies are often preliminary and require further investigation to be confirmed and generalized.

**Important Considerations:**

* **Limited clinical evidence:** There is currently limited clinical evidence available to support the effectiveness and safety of AOD-9604 in treating cancer. Its use is typically considered experimental and off-label.

* **Potential side effects:** The potential side effects of AOD-9604 are not fully understood and are likely to be related to the specific mechanisms of action being studied.

* **Not FDA-approved:** AOD-9604 is not approved by the FDA for any medical use. Its use should be strictly under the supervision of a qualified healthcare professional.

* **Ethical considerations and patient rights:** Patients should carefully discuss the risks and benefits of any experimental treatment with their doctor, and make informed decisions about their health care. Consult with a healthcare professional about your individual needs.

**In Summary:**

AOD-9604 is a promising compound under investigation for its potential anti-cancer effects. However, its effectiveness and safety require further, robust scientific validation through clinical trials before it can be considered a standard treatment option. Always consult with a medical professional before using any experimental or off-label treatments.

Size: 5mg
Contents: AOD 9604 (5mg)
Form: Lyophilized powder
Purity: >99%
SKU: P-AOD9604-5

Category:
Description

AOD 9604 Peptide

AOD 9604 peptide is a synthetic analog of growth hormone designed with the intention of mitigating obesity and aiding weight loss. The peptide is a modified fragment of the growth hormone where the last 16 amino acids (176-191) have been reproduced as a specific peptide, called GH Fragment 176-191 or simply AOD 9604. It also has a tyrosine residue to replace the first amino acid at the N-terminus, which researchers consider to help increase the stability of the peptide.(1)

More specifically, AOD 9604 is considered the lipolytic fragment of GH as different parts of the GH molecule appease to have different potentials. For instance, studies suggest that out of its 191 amino acid structure “the N-terminal region exhibits an insulin-potentiating action, while amino acids 108 – 129 of hGH were found to evoke high mitogenic responses.(2)

AOD 9604

AOD 9604 peptide was developed in the 1990s in an effort to develop proteins which might exhibit anti-obesity properties similar to Growth Hormone (hGH). Rigorous scientific studies and experiments have since been conducted to determine the potential action of AOD 9604 in lipolysis.(1) Lipolysis is a term to describe the process through which stored fats or triglycerides in fat cells are broken down into glycerol and free fatty acids, which may be used as an energy source by other cells. Enzymes such as lipase appear to play a critical role in this process, helping in the breakdown of these fats. It’s possible that AOD9604 may influence the fat cells and lipolytic receptors, particularly given its observed association with changes in weight and fat in murine models. Research study findings indicate that the fragment seems to have the capacity to amplify lipolytic sensitivity following its introduction. Furthermore, the study hypothesizes a potential interaction of AOD9604 with the beta-adrenergic pathway, especially concerning the beta(3)-adrenergic receptors (beta(3)-AR), which are considered to be key lipolytic receptors found in fat cells. While it is not entirely clear, the expression level of beta(3)-AR RNA, the primary lipolytic receptor in fat cells, was observed to increase in the presence of AOD 9604. This could possibly suggest that the peptide might be playing a role in enhancing the sensitivity of these lipolytic receptors, potentially making them more responsive to lipolytic stimuli. However, it is essential to note that while the peptide appears to elevate the expression of beta(3)-AR, it may not act directly through the beta(3)-AR to induce its potential lipolytic action.

Scientists and researchers have suggested that the modified portion of the hGH in the AOD 9604 peptide may be responsible for significantly inducing the fat burning process, possibly without stimulating the production of Insulin-like Growth Factor IGF 1, as opposed to the natural growth hormone.

Chemical Makeup

Molecular Formula: C78H123N23O23S2
Molecular Weight: 1815.12 g/mol
Other Known Titles: Tyr-hGH Fragment 177-191

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